Mechanisms of Antimicrobial Resistance in Pathogens

Mechanisms of Antimicrobial Resistance in Pathogens focus on how microorganisms such as bacteria, viruses, fungi, and parasites evolve to survive exposure to antimicrobial agents. These resistance mechanisms reduce the effectiveness of drugs, making infections difficult to treat and increasing the risk of disease spread and complications.

One of the primary mechanisms is enzymatic degradation or modification of antibiotics, where pathogens produce enzymes (such as beta-lactamases) that inactivate antimicrobial drugs before they can act. Another important mechanism is alteration of drug targets, where genetic mutations modify the structure of microbial proteins or cellular components, preventing the drug from binding effectively.

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